This site has limited support for your browser. We recommend switching to Edge, Chrome, Safari, or Firefox.

Free US shipping on orders over $50

Free samples with every order

hand cream for dry chapped skin needing hydration fast drying probiotic luxury hand cream
premium hand care bundle with luxury hand creams
hand care bundles for dry chapped hand needing immediate hydration anti-aging and luxury
luxury hand care kit for dry irritated skin needing moisture and non greasy hydration

Premium Hand Care Bundle


all skin types

All Skin Types

dry skin


sensitive skin

Sensitive Skin

healthy skin

Healthy Aging


2022 Beauty Innovation Awards Winner
2022 Refinery29 Beauty Innovator Award Winner


Celebrate self-care and soft hands with our award-winning hand creams. Pamper yourself or a special someone with two luxurious creams that will hydrate and soothe their skin all year round. Infused with probiotic bioferments to hydrate, nourish and lock in moisture.

Why It Works

Indulgent Nourishment: Our luxury hand cream harnesses the power of vitamin B5, shea butter, and baobab oil, ensuring deeply moisturized and rejuvenated skin.

Advanced Probiotic Protection: Experience the revolutionary Triple Probiotic Blend that mimics your skin's natural moisture, making this the ultimate anti-aging hand cream for optimal hydration.

Soothing & Fortifying: Combat signs of aging and external stressors with allantoin, echinacea stem cells, and cloudberry antioxidants, while meadowfoam seed oil reinforces the skin's natural barrier for prolonged hydration.

Probiotic Bioferments

Prebiotics: Inulin, Alpha-Glucan Oligosaccharide

Probiotics: Lactobacillus Ferment Lysate, Lactobacillus Ferment Lysate Filtrate

Postbiotics: Saccharomyces Lysate, Valine (L), Glycine, Glutamic Acid (L), Threonine

cruelty free certified by leaping bunny no animal testing
cruelty free certified vegan products PETA approved
Carbon-neutral shipping with Shopify Planet
Carbon-neutral shipping on all orders

Hand Care Essentials

Featured In

nuebiome probiotic face serums for dull skin


Pre-, Pro-, & Postbiotics: Help to soothe and calm irritated skin, reduce redness, and enhance skin's natural moisturizing factors.

Squalane: helps to hydrate the skin and retain moisture, making it soft and supple.

Vitamin E: Antioxidant that aids in protecting skin from oxidative stress.

Saccharide Isomerate: Maize derived moisturizing factor that rebalances microbial activity and stimulates epidermal barrier building blocks to reinforce and restore healthy looking skin.

clean non-toxic probiotic skincare


Our strict standards exclude health offenders like parabens, phthalates, sulfates, PEGs, chemical sunscreens and EDTA to name a few.

See our 100+ skincare ingredients to avoid.

nuebiome  nontoxic skincare beauty ingredients


We've gone even further to exclude controversial ingredients like irradiated bacteria, drying alcohols, mineral oils, animal fats, all silicone derivatives like dimethicone, artificial colors and fragrances due to their negative effects on maintaining the skin's balance.


Clean. Effective. Biocompatible.

We're constantly working to formulate the highest quality clean skincare collection that's wholly bioferment and plant-derived.

Effective Means High Performing

Our clinician-developed formulas use only clinically proven high quality probiotic ingredients at active levels.

Clean Means Safe

Our formulas are made without ingredients shown or suspected to harm human health. 100+ toxic skincare ingredients to avoid.

pH Means Equilibrium

We formulate with special attention to the natural pH of the skin barrier and acid mantle. When pH is optimized the skin is better able to defend against pathogenic microorganisms and recognize compatible ingredients.

Made in the USA

We are designed, formulated and produced in the USA at an FDA certified facility.

Grounded in Research

Every ingredient is evaluated for functionality, safety and performance.


We source the highest quality plant-based and plant-derived ingredients.

nuebiome probiotic skincare serums with natural clean ingredients


Unique fermentation and filtration process isolating potent bacterial elements to enhance skin conditioning.


Our hand care features a nutrient-rich bioferment blend, conditioning skin and locking in moisture.

Customer Reviews

Based on 87 reviews
Elizabeth B.
Hand cream

Cream is very nice. Nice smell and leaves hands very smooth.

Olivia O.
Fantastic Deep Hydration

The deep hand treatment is fantastic, offering deep hydration without greasiness. The amaretto hand remedy is a nice complement for daytime use, though I prefer unscented options.

Ulysses U.
Best Holiday Gift Received

This premium hand care bundle was among the best gifts I received this holiday. It's been especially useful for combating the harsh winter conditions. The deep treatment offers unparalleled moisture, and the amaretto remedy is perfect for maintaining that hydration throughout the day. Both products have exceeded my expectations and have made a noticeable difference in the health and appearance of my hands.

Kayla K.
Subtle Scent, Major Impact

The amaretto scent is subtle and divine, making daily application something to look forward to. The deep treatment at night seals in the moisture, ensuring I wake up with soft, supple hands. Bought these as gifts and kept one for myself—best decision!

Sam T.
Dynamic Duo

A dynamic duo for hand care. The deep treatment restores my hands overnight, and the amaretto remedy is a delightful daytime protector.

Taylor T.
Best Holiday Investment

The deep hand treatment from this bundle is incredible for nighttime recovery, providing my hands with the intensive care they need. The amaretto hand remedy is a wonderful complement for daytime use, keeping my hands protected against the dry winter air. This bundle was a self-purchase this holiday season, and it's been the best investment in my hand care routine.

Jesse J.
Pleasant Winter Surprise

I was pleasantly surprised by how well these two products worked together. Gifting them to myself this holiday was a stroke of genius. My hands have never felt or looked better, even in the midst of winter.

Noah N.
Winter Essential

The premium hand care bundle is a winter essential. It keeps my hands moisturized and soft, even on the coldest days. Both products are staples in my daily routine now.

Sam S.
The Gift That Keeps on Giving

Received this premium bundle as a holiday gift and it's truly the gift that keeps on giving. The combination of deep overnight treatment and daytime protection has transformed my winter hand care routine. The amaretto hand remedy is especially delightful to use with its subtle scent and effective hydration.

Riley S.
Love This Bundle

Love, love, love this bundle! The deep treatment at night and the amaretto during the day have made such a difference. My hands are softer and healthier than ever.