This site has limited support for your browser. We recommend switching to Edge, Chrome, Safari, or Firefox.

Free US shipping on orders over $50

Free samples with every order

hand cream for dry chapped skin needing hydration fast drying probiotic luxury hand cream
premium hand care bundle with luxury hand creams
hand care bundles for dry chapped hand needing immediate hydration anti-aging and luxury
luxury hand care kit for dry irritated skin needing moisture and non greasy hydration

Premium Hand Care Bundle


all skin types

All Skin Types

dry skin


sensitive skin

Sensitive Skin

healthy skin

Healthy Aging


2024 NewBeauty Award - Best Hand Cream
2022 Beauty Innovation Awards Winner
2022 Refinery29 Beauty Innovator Award Winner


Celebrate self-care and soft hands with our award-winning hand creams. Pamper yourself or a special someone with two luxurious creams that will hydrate and soothe skin all year round. Infused with probiotic bioferments to hydrate, nourish and lock in moisture.

Why It Works

Indulgent Nourishment: Our luxury hand cream harnesses the power of vitamin B5, shea butter, and baobab oil, ensuring deeply moisturized and rejuvenated skin.

Advanced Probiotic Protection: Experience the revolutionary Triple Probiotic Blend that mimics your skin's natural moisture, making this the ultimate anti-aging hand cream for optimal hydration.

Soothing & Fortifying: Combat signs of aging and external stressors with allantoin, echinacea stem cells, and cloudberry antioxidants, while meadowfoam seed oil reinforces the skin's natural barrier for prolonged hydration.

Probiotic Bioferments

Prebiotics: Inulin, Alpha-Glucan Oligosaccharide

Probiotics: Lactobacillus Ferment Lysate, Lactobacillus Ferment Lysate Filtrate

Postbiotics: Saccharomyces Lysate, Valine (L), Glycine, Glutamic Acid (L), Threonine

cruelty free certified by leaping bunny no animal testing
cruelty free certified vegan products PETA approved
Carbon-neutral shipping with Shopify Planet
Carbon-neutral shipping on all orders

Hand Care Essentials

Featured In

nuebiome probiotic face serums for dull skin


Pre-, Pro-, & Postbiotics: Help to soothe and calm irritated skin, reduce redness, and enhance skin's natural moisturizing factors.

Squalane: helps to hydrate the skin and retain moisture, making it soft and supple.

Vitamin E: Antioxidant that aids in protecting skin from oxidative stress.

Saccharide Isomerate: Maize derived moisturizing factor that rebalances microbial activity and stimulates epidermal barrier building blocks to reinforce and restore healthy looking skin.

clean non-toxic probiotic skincare


Our strict standards exclude health offenders like parabens, phthalates, sulfates, PEGs, chemical sunscreens and EDTA to name a few.

See our 100+ skincare ingredients to avoid.

nuebiome  nontoxic skincare beauty ingredients


We've gone even further to exclude controversial ingredients like irradiated bacteria, drying alcohols, mineral oils, animal fats, all silicone derivatives like dimethicone, artificial colors and fragrances due to their negative effects on maintaining the skin's balance.


Clean. Effective. Biocompatible.

We're constantly working to formulate the highest quality clean skincare collection that's wholly bioferment and plant-derived.

Effective Means High Performing

Our clinician-developed formulas use only clinically proven high quality probiotic ingredients at active levels.

Clean Means Safe

Our formulas are made without ingredients shown or suspected to harm human health. 100+ toxic skincare ingredients to avoid.

pH Means Equilibrium

We formulate with special attention to the natural pH of the skin barrier and acid mantle. When pH is optimized the skin is better able to defend against pathogenic microorganisms and recognize compatible ingredients.

Made in the USA

We are designed, formulated and produced in the USA at an FDA certified facility.

Grounded in Research

Every ingredient is evaluated for functionality, safety and performance.

skincare and hand creams with probiotics


We source the highest quality plant-based and plant-derived ingredients.

nuebiome probiotic skincare serums with natural clean ingredients


Unique fermentation and filtration process isolating potent bacterial elements to enhance skin conditioning.

skincare for hands and face


Our hand care features a nutrient-rich bioferment blend, conditioning skin and locking in moisture.